Azathioprine
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Prevent transplant rejection
Children and adults: Initial dose of 2–5 mg/kg/24 hr IV or PO, with a maintenance dose of 1–3 mg/kg/24 hr
Treatment of autoimmune disease (e.g., lupus, arthritis, nephrotic syndrome)
Inhibits synthesis of DNA, RNA, and proteins. Antagonizes purine metabolism.
Adults: 1 mg/kg/24 hr × 6–8 wk.
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